Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | KAT7 | O95251 | 12/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 12/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | KAT6B | Q8WYB5 | 3/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949603 | 0.93 | KCNH2 (0.45) | GRIN1GRIN2BPDE4BKAT7KAT6A | |
| SCHEMBL28949563 | 0.89 | PDE4B (0.46) | GRIN1GRIN2BPDE4BKAT7KAT6A | |
| SCHEMBL28825511 | 0.86 | PDE4B (0.48) | GRIN1GRIN2BPDE4BKAT7KAT6A | |
| SCHEMBL28694731 | 0.85 | GRIN2B (0.43) | GRIN1GRIN2BPDE4BKAT7KAT6A | |
| SCHEMBL28964549 | 0.84 | GAA (0.43) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL28825491 | 0.83 | PDE4B (0.49) | GRIN1GRIN2BPDE4B | |
| SCHEMBL28825498 | 0.81 | KCNH2 (0.48) | GRIN1GRIN2BGAAMAPT | |
| SCHEMBL28825559 | 0.80 | PDE4B (0.48) | GRIN1GRIN2BPDE4BKAT7KAT6A | |
| SCHEMBL28825499 | 0.80 | KCNH2 (0.47) | GRIN1GRIN2BGAAMAPT | |
| SCHEMBL28825510 | 0.75 | GRIN2B (0.52) | GRIN1GRIN2BGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |