Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634898 | 0.87 | LMNA (0.74) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL8634895 | 0.87 | LMNA (0.74) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27178058 | 0.85 | CA1 (0.75) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27178061 | 0.85 | CA1 (0.75) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL17560861 | 0.84 | LMNA (1.00) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27178238 | 0.83 | CA1 (0.68) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27178246 | 0.83 | CA1 (0.68) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27177914 | 0.83 | NPC1 (0.72) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27178212 | 0.83 | NPC1 (0.72) | LMNACYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27177853 | 0.83 | NPC1 (0.72) | LMNACYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130843-A | Benzyl hydrazone compound and preparation method and uses thereof | UNIV CHINA AGRICULTURAL | 2015-12-09 | — | — | CN | disclosed |