Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930351 | 0.86 | ALDH1A1 (0.33) | HTR6TLR8MAPTGAAALDH1A1 | |
| SCHEMBL15660148 | 0.82 | KCNH2 (0.35) | TSHRSMN1; SMN2KCNH2SIGMAR1CYP1A2 | |
| SCHEMBL17529753 | 0.78 | CA1 (0.43) | TLR8ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL2848684 | 0.77 | — | — | |
| SCHEMBL15658031 | 0.76 | BCHE (0.36) | MAPTGAAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2879314 | 0.76 | KCNH2 (0.39) | ALDH1A1TP53TSHRKCNH2SIGMAR1 | |
| SCHEMBL11196033 | 0.76 | MAPT (0.34) | HTR6TLR8MAPTGAAALDH1A1 | |
| SCHEMBL11196031 | 0.76 | MAPT (0.34) | HTR6TLR8MAPTGAAALDH1A1 | |
| SCHEMBL1726391 | 0.75 | TSHR (0.36) | TLR8MAPTALDH1A1TP53TSHR | |
| SCHEMBL5443955 | 0.74 | CYP1A2 (0.38) | MAPTTP53TSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109819649-A | (1S, 4S) -4- (2- (((3S, 4R) -3- fluorine tetrahydro -2H- pyrans -4- base) amino) -8- ((2,4,6- trichlorophenyl) amino) -9H- purine -9- base) and -1- hexahydrotoluene -1- formamide solid form and its application method | 西格诺药品有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-105324381-A | Pharmaceutical formulations, procedures, solid forms and methods of use relating to 1-ethyl-7- (2-methyl-6- (1H-1,2, 4-triazol-3-yl) pyridin-3-yl) -3, 4-dihydropyrazino [2,3-b ] pyrazin-2 (1H) -one | SIGNAL PHARM LLC | 2016-02-10 | — | — | CN | disclosed |