Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.57 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407782 | 1.00 | PNMT (0.57) | PNMTLIPGNR1H2NR1H3BID | |
| SCHEMBL28103115 | 1.00 | PNMT (0.57) | PNMTLIPGNR1H2NR1H3BID | |
| SCHEMBL14836704 | 1.00 | PNMT (0.57) | PNMTLIPGNR1H2NR1H3BID | |
| SCHEMBL1449245 | 1.00 | PNMT (0.57) | PNMTLIPGNR1H2NR1H3BID | |
| SCHEMBL6672769 | 1.00 | PNMT (0.57) | PNMTLIPGNR1H2NR1H3BID | |
| SCHEMBL6675428 | 1.00 | PNMT (0.57) | PNMTLIPGNR1H2NR1H3BID | |
| SCHEMBL29911116 | 1.00 | PNMT (0.57) | PNMTLIPGNR1H2NR1H3BID | |
| Bromide SCHEMBL29130618 | 0.98 | PNMT (0.55) | PNMTLIPGNR1H2NR1H3BID | |
| SCHEMBL5823386 | 0.98 | PNMT (0.58) | PNMTLIPGNR1H2NR1H3BID | |
| Bromide SCHEMBL28532857 | 0.97 | PNMT (0.54) | PNMTLIPGNR1H2NR1H3BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330508-B | One kind 3 is monosubstituted or 3,6 2 replace fluorene derivative and its preparation method and application | 亚培烯科技（杭州）有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-107020024-A | A kind of preparation method of water-oil separationg film | 福建师范大学 | 2017-08-08 | — | — | CN | disclosed |
| CN-105669902-A | Novel cycloolefin copolymer catalyst and synthetic method thereof | 魏东初 | 2016-06-15 | — | — | CN | disclosed |
| CN-105348330-A | 3 mono-substituted or 3,6 bis-substituted fluorenyl metalloscene and preparation method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-105330508-A | 3-monosubstituted or 3,6-disubstituted fluorene derivative and preparing method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |