Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 12/20 | 0.82 |
| ▸ | ACVR1B | P36896 | 3/20 | 0.82 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.80 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.80 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.80 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.77 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.77 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.77 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.77 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139175 | 0.92 | TGFBR1 (0.79) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL7590309 | 0.91 | TGFBR1 (0.78) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL373558 | 0.91 | TGFBR1 (1.00) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL4075751 | 0.89 | TGFBR1 (0.69) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL373802 | 0.89 | TGFBR1 (1.00) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL373248 | 0.89 | TGFBR1 (1.00) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL4153862 | 0.89 | TGFBR1 (0.85) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL23352241 | 0.88 | TGFBR1 (0.73) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| SCHEMBL2617116 | 0.88 | TGFBR1 (0.84) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 | |
| Sb-431542 SCHEMBL310028 | 0.88 | TGFBR1 (1.00) | TGFBR1ACVR1BMAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658788-A | Method for preparing dopaminergic neurons | 武田药品工业株式会社 | 2016-06-08 | — | — | CN | disclosed |