Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642893 | 0.81 | — | — | |
| SCHEMBL28825994 | 0.76 | ESR2 (0.44) | MEN1KMT2AESR2BCL2L1 | |
| SCHEMBL29941648 | 0.69 | FYN (0.36) | — | |
| SCHEMBL17177458 | 0.68 | — | — | |
| SCHEMBL16020439 | 0.66 | HSD17B1 (0.58) | ALOX5ESR1MEN1KMT2AESR2 | |
| SCHEMBL28091062 | 0.66 | HSD17B1 (0.58) | ALOX5ESR1MEN1KMT2AESR2 | |
| SCHEMBL30920926 | 0.64 | FLT3 (0.31) | KMT2A | |
| SCHEMBL1513558 | 0.64 | HSD17B1 (0.62) | ALOX5ESR1MEN1KMT2AESR2 | |
| SCHEMBL1513721 | 0.64 | HSD17B1 (0.58) | ALOX5ESR1MEN1KMT2AESR2 | |
| SCHEMBL27515726 | 0.64 | ESR1 (0.43) | ALOX5ESR1MEN1KMT2AESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431422-A | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2016-03-23 | — | — | CN | disclosed |