Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21955665 | 0.98 | MAPT (0.40) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL16584004 | 0.93 | SKP2 (0.41) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL30014752 | 0.79 | ALOX5 (0.40) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL28211588 | 0.79 | ALOX5 (0.40) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL28109878 | 0.79 | TYR (0.42) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL28211164 | 0.77 | TYR (0.47) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL28211073 | 0.77 | TYR (0.41) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL18428550 | 0.77 | ALOX5 (0.47) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL841582 | 0.77 | ALOX5 (0.47) | MAPTALOX5CYP3A4TYRMEN1 | |
| SCHEMBL15486053 | 0.77 | ALOX5 (0.47) | MAPTALOX5CYP3A4TYRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570630-B | Nitrogen heterocyclic derivative and the application in medicine thereof | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |