SCHEMBL2882733

SCHEMBL2882733

CCCCCNS([O])(=O)=O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.62
CA2 P00918 5/20 0.59
CA1 P00915 4/20 0.59
CA12 O43570 2/20 0.59
CA7 P43166 2/20 0.59
CA14 Q9ULX7 2/20 0.59
EPHX1 P07099 1/20 0.56
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
CA9 Q16790 1/20 0.47
RELA Q04206 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5256485 0.97 PPARA (0.67) PPARACA2CA1CA12CA7
SCHEMBL27500497 0.97 PPARA (0.67) PPARACA2CA1CA12CA7
SCHEMBL245387 0.92
SCHEMBL4563383 0.83 PPARA (0.86) PPARACA2CA1CA12CA7
SCHEMBL1076805 0.81 CA2 (0.61) PPARACA2CA1CA12CA7
SCHEMBL694651 0.81 PPARA (0.60) PPARACA2CA1CA12CA7
SCHEMBL10892940 0.81 PPARA (0.91) PPARACA2CA1CA12CA7
SCHEMBL3792249 0.81 PPARA (0.91) PPARACA2CA1CA12CA7
SCHEMBL327308 0.81 PPARA (0.60) PPARACA2CA1CA12CA7
SCHEMBL9285865 0.81 PPARA (0.91) PPARACA2CA1CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103391916-B Dehydroabietic acid derivative, process for producing the same, and process for producing 12-carboxy dehydroabietic acid derivative FUJIFILM CORP. (JP) 2015-09-16 CN claimed
CN-103391916-A Dehydroabietic acid derivative, process for producing the same, and process for producing 12-carboxy dehydroabietic acid derivative FUJI FILM CORP 2013-11-13 CN claimed
CN-102379872-A Compounds, compositions and methods of inhibiting a-synuclein toxicity WHITEHEAD BIOMEDICAL INST 2012-03-21 CN claimed
CN-102351880-A Cyanoaminoquinolones and tetrazoloaminoquinolones as GSK-3 inhibitors KYORIN SEIYAKU KK 2012-02-15 CN claimed
CN-101855228-A Cyanoaminoquinolones and tetrazoloaminoquinolones as GSK-3 inhibitors ACTIVX BIOSCIENCES INC 2010-10-06 CN claimed
WO-2010012793-A1 FUNGICIDE AMINOTHIAZOLE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2010-02-04 WO claimed
CN-101611008-A C3A receptor modulators and methods of use thereof ENCYSIVE PHARMACEUTICALS INC (US) 2009-12-23 CN claimed
EP-1976839-A2 COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING Foldrx Pharmaceuticals, Inc. (US) 2008-10-08 EP claimed
CN-101094833-A Tetrapeptide analogs IDUN PHARMACEUTICALS INC (US) 2007-12-26 CN claimed
CN-101060839-A Compounds, compositions and methods for inhibiting alpha-synuclein toxicity WHITEHEAD BIOMEDICAL INST (US) 2007-10-24 CN claimed
WO-2007089548-A2 COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING FOLDRX PHARMACEUTICALS, INC. (US) 2007-08-09 WO claimed
EP-1802303-A2 COMPOUNDS, COMPOSITIONS AND METHODS OF INHIBITING A-SYNUCLEIN TOXICITY WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2007-07-04 EP claimed
CN-1984883-A Substituted n-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies PROTEOTECH INC (US) 2007-06-20 CN claimed
WO-2006034003-A2 COMPOUNDS, COMPOSITIONS AND METHODS OF INHIBITING A-SYNUCLEIN TOXICITY WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2006-03-30 WO claimed
CN-103391916-B Dehydroabietic acid derivative, process for producing the same, and process for producing 12-carboxy dehydroabietic acid derivative FUJIFILM CORP. (JP) 2015-09-16 CN disclosed
CN-102351880-B Cyanoaminoquinolones and tetrazoloaminoquinolones as GSK-3 inhibitors KYORIN SEIYAKU KK 2014-11-12 CN disclosed
CN-103391916-A Dehydroabietic acid derivative, process for producing the same, and process for producing 12-carboxy dehydroabietic acid derivative FUJI FILM CORP 2013-11-13 CN disclosed
US-6096735-A Benzoheterocyclic derivatives OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 2000-08-01 US disclosed
EP-0765314-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-02 EP disclosed
WO-1995034540-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-12-21 WO disclosed