SCHEMBL28827339

SCHEMBL28827339

CCCCCCC1CC1(Br)Br

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
EPHX1 P07099 1/20 0.40
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
ALOX5 P09917 1/20 0.34
GBA1 P04062 3/20 0.33
CYP1A2 P05177 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
SPHK1 Q9NYA1 5/20 0.32
SPHK2 Q9NRA0 3/20 0.32
GUSB P08236 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11859588 0.76 ALDH1A1 (0.43) ALDH1A1EPHX1TSHRTHRBALOX5
SCHEMBL11033685 0.75 ALDH1A1 (0.41) ALDH1A1EPHX1TSHRTHRBALOX5
SCHEMBL22471680 0.74 ALDH1A1 (0.41) ALDH1A1EPHX1TSHRTHRBALOX5
SCHEMBL17351132 0.74 ALDH1A1 (0.41) ALDH1A1EPHX1TSHRTHRBGBA1
SCHEMBL17536922 0.73 ALDH1A1 (0.39) ALDH1A1EPHX1TSHRTHRBALOX5
Ammonia Solution, Strong SCHEMBL22283017 0.73 ALDH1A1 (0.39) ALDH1A1EPHX1TSHRTHRBALOX5
SCHEMBL5986589 0.73 ALDH1A1 (0.39) ALDH1A1EPHX1TSHRTHRBALOX5
SCHEMBL24769050 0.65
SCHEMBL19063365 0.64 TSHR (0.57) ALDH1A1EPHX1TSHRTHRB
Decane SCHEMBL10731325 0.62 TSHR (0.80) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114828958-A Cycloalkyl-containing carboxylic acids and use thereof 里米诺生物科学有限公司 2022-07-29 CN disclosed