SCHEMBL28827360

SCHEMBL28827360

CCCCCCCCCCC(CCCCCCCC)COc1cccc2cc3c(ccc4c5cc6ccccc6cc5ccc34)cc12.C[Sn](C)(C)Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.36
KMT2A Q03164 3/20 0.36
MAPK1 P28482 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
MEN1 O00255 2/20 0.36
GPBAR1 Q8TDU6 2/20 0.36
CYP2C9 P11712 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
HIF1A Q16665 1/20 0.36
GMNN O75496 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
ALOX5 P09917 1/20 0.36
HPGD P15428 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29147666 0.96 HTR1B (0.39) HTR1BKMT2AMAPK1CYP1A2CYP2C19
Anthracene SCHEMBL28827369 0.90 HTR1B (0.43) HTR1BKMT2AMAPK1CYP1A2CYP2C19
SCHEMBL28827376 0.90 HTR1B (0.43) HTR1BKMT2AMAPK1CYP1A2CYP2C19
SCHEMBL3414896 0.80 CA2 (0.44) HTR1BKMT2ACYP1A2CYP2C19MEN1
Anthracene SCHEMBL28584681 0.80 CA2 (0.44) HTR1BKMT2ACYP1A2CYP2C19MEN1
SCHEMBL18837359 0.78 HTR1B (0.52) HTR1BKMT2AMAPK1CYP1A2CYP2C19
SCHEMBL17912798 0.74 KCNA3 (0.53) HTR1BKMT2AMEN1CYP2C9CYP3A4
SCHEMBL17912877 0.74 KCNA3 (0.53) HTR1BKMT2AMEN1CYP2C9CYP3A4
SCHEMBL20678360 0.74 KCNA3 (0.53) HTR1BKMT2AMEN1CYP2C9CYP3A4
SCHEMBL585194 0.74 KCNA3 (0.53) HTR1BKMT2AMEN1CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957237-A D (A-Ar) taking alkyl modified vat orange 3 as central nucleus 2 Synthesis and application of small organic molecules 东华理工大学 2022-08-30 CN disclosed