Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617053 | 0.80 | MAPT (0.57) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL1879421 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EKMT2AMAPTGRM1 | |
| SCHEMBL1767710 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6904519 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28827439 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28950007 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL1886013 | 0.76 | KDM4E (0.78) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL14575270 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL31222339 | 0.75 | MEN1 (0.53) | ALDH1A1KDM4EKMT2AMEN1GRM1 | |
| SCHEMBL31544141 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957112-B | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114957112-A | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | disclosed |