Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27869788 | 0.85 | SLC18A3 (0.39) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL30661790 | 0.82 | KCNH2 (0.38) | CHRM3 | |
| SCHEMBL28620717 | 0.82 | KCNH2 (0.38) | CHRM3 | |
| SCHEMBL29116010 | 0.82 | KCNH2 (0.38) | CHRM3 | |
| SCHEMBL28615920 | 0.82 | KCNH2 (0.38) | CHRM3 | |
| SCHEMBL28065007 | 0.78 | CHRM3 (0.38) | RIPK1CHRM3CHRM2CHRM1 | |
| SCHEMBL16401685 | 0.76 | HRH1 (0.37) | — | |
| SCHEMBL22473490 | 0.76 | IDO1 (0.31) | — | |
| SCHEMBL28046408 | 0.75 | TACR1 (0.44) | RIPK1 | |
| SCHEMBL27630868 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-B | Piperidinylindole derivatives and their use as complement factor B inhibitors | 诺华股份有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |