Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828167 | 0.78 | RIPK1 (0.40) | CHRM3CHRM2CHRM1RIPK1 | |
| SCHEMBL27722903 | 0.78 | RIPK1 (0.40) | RIPK1NPC1MAPTPKMLMNA | |
| SCHEMBL27869789 | 0.76 | SLC6A1 (0.42) | KDM1AMAOAMAPTCHRNA7 | |
| Tert-Butyl Formate SCHEMBL28065009 | 0.74 | KDM1A (0.34) | CHRM3CHRM2CHRM1RIPK1KDM1A | |
| SCHEMBL24363923 | 0.73 | CHRNA7 (0.46) | KDM1AMAOACHRNA7LMNA | |
| SCHEMBL16400486 | 0.73 | KDM1A (0.42) | KDM1AMAOACHRNA7 | |
| SCHEMBL3438950 | 0.73 | CHRNA7 (0.46) | KDM1AMAOACHRNA7LMNA | |
| SCHEMBL2707339 | 0.73 | KDM1A (0.42) | KDM1AMAOACHRNA7 | |
| SCHEMBL29477503 | 0.73 | CHRNA7 (0.46) | KDM1AMAOACHRNA7LMNA | |
| SCHEMBL30661773 | 0.73 | KDM1A (0.39) | KDM1AMAOAMAPTCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |