Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828488 | 0.96 | ACACB (0.37) | RARBRARAPPARDALDH1A1 | |
| SCHEMBL28950180 | 0.93 | NR1H4 (0.41) | PPARDSMN1; SMN2HTR2A | |
| SCHEMBL29121247 | 0.91 | PARP10 (0.39) | PPARDHPGDALDH1A1 | |
| SCHEMBL28828590 | 0.91 | PARP10 (0.39) | PPARDHPGDALDH1A1 | |
| SCHEMBL28828573 | 0.90 | CHEK1 (0.41) | RARBRARAPPARD | |
| SCHEMBL28828468 | 0.90 | PARP1 (0.36) | RARBRARAPPARDALDH1A1HTR2A | |
| SCHEMBL29121254 | 0.89 | RARB (0.40) | RARBRARAPPARDMEN1KMT2A | |
| SCHEMBL28828679 | 0.87 | SLC13A5 (0.40) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28828438 | 0.87 | FYN (0.40) | RARBRARAPPARD | |
| SCHEMBL28828547 | 0.87 | MPL (0.41) | RARBRARAHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |