Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL29140943 | 1.00 | HTT (0.56) | HTTTDP1POLBAPEX1TP53 | |
| Terephthalic Acid SCHEMBL27660838 | 0.98 | HTT (0.54) | HTTTDP1POLBAPEX1TP53 | |
| Terephthalic Acid SCHEMBL29140957 | 0.95 | HTT (0.52) | HTTTDP1POLBAPEX1TP53 | |
| Terephthalic Acid SCHEMBL2186287 | 0.94 | HTT (0.50) | HTTTDP1POLBAPEX1TP53 | |
| Terephthalic Acid SCHEMBL28361003 | 0.93 | HTT (0.55) | HTTTDP1POLBAPEX1TP53 | |
| SCHEMBL28189361 | 0.91 | HTT (0.52) | HTTTDP1POLBAPEX1TP53 | |
| Terephthalic Acid SCHEMBL29140933 | 0.90 | HTT (0.51) | HTTTDP1POLBAPEX1TP53 | |
| SCHEMBL27865834 | 0.90 | HTT (0.50) | HTTTDP1POLBAPEX1TP53 | |
| Terephthalic Acid SCHEMBL27960052 | 0.88 | HTT (0.49) | HTTTDP1POLBAPEX1TP53 | |
| Terephthalic Acid SCHEMBL23910546 | 0.86 | HTT (0.55) | HTTTDP1POLBAPEX1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119895007-A | Moisture-curable polyurethane hot melt adhesive compositions | 汉高股份有限及两合公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-118613563-A | Reactive hot melt adhesive composition and use thereof | 汉高股份有限及两合公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118355088-A | Moisture-curable polyurethane hot melt adhesive compositions | 汉高股份有限及两合公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114008165-B | Moisture curable polyurethane hot melt adhesive compositions with low levels of diisocyanate monomer | H.B.富乐公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116635501-A | Oil resistant adhesive composition | 汉高股份有限及两合公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114846107-A | Polyurethane hot melt adhesive composition and method for preparing same | 汉高股份有限及两合公司 | 2022-08-02 | — | — | CN | disclosed |