Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882964 | 1.00 | KDM1A (0.43) | KDM1AHTR2CHCRTR2HTR6HTR2A | |
| SCHEMBL2882755 | 0.87 | KDM1A (0.41) | KDM1AHTR2CHTR6HTR2AHTR2B | |
| SCHEMBL2882754 | 0.87 | KDM1A (0.41) | KDM1AHTR2CHTR6HTR2AHTR2B | |
| SCHEMBL2880286 | 0.81 | KDM1A (0.44) | KDM1AHTR2CHTR2AHTR2BSSTR1 | |
| SCHEMBL2880289 | 0.81 | KDM1A (0.44) | KDM1AHTR2CHTR2AHTR2BSSTR1 | |
| SCHEMBL2883024 | 0.77 | HTR2C (0.50) | KDM1AHTR2CHTR2AHTR2BSSTR1 | |
| SCHEMBL2877892 | 0.75 | HTR2C (0.47) | KDM1AHTR2CHTR2AHTR2B | |
| SCHEMBL2883379 | 0.72 | HTR2C (0.58) | KDM1AHTR2CHTR2AHTR2B | |
| SCHEMBL2883946 | 0.69 | HTR2C (0.54) | KDM1AHTR2CHTR2AHTR2B | |
| SCHEMBL21209332 | 0.69 | KCNH2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855294-B2 | Cycloalkanopyridine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20070191419-A1 | Cycloalkanopyridine derivative | MSD K.K. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1726590-A1 | CYCLOALKANOPYRIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191419-A1 | Cycloalkanopyridine derivative | OPRL1, OPRK1, AVPR2 | KDM1A 3484/4885HTR2C 699/4885HCRTR2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.