Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227343 | 0.87 | HTR2C (0.61) | HTR2CKDM1AMAOAMAOBSLC6A2 | |
| SCHEMBL6227345 | 0.87 | HTR2C (0.61) | HTR2CKDM1AMAOAMAOBSLC6A2 | |
| SCHEMBL2437089 | 0.87 | HTR2C (0.54) | HTR2CKDM1AMAOAMAOBNPC1 | |
| SCHEMBL15797925 | 0.87 | HTR2C (0.54) | HTR2CKDM1AMAOAMAOBNPC1 | |
| SCHEMBL2435013 | 0.86 | HTR2C (0.59) | HTR2CKDM1AMAOAMAOBMIF | |
| SCHEMBL2091037 | 0.84 | HTR2C (0.62) | HTR2CKDM1AMAOAMAOBSLC6A2 | |
| SCHEMBL2090322 | 0.84 | HTR2C (0.62) | HTR2CKDM1AMAOAMAOBSLC6A2 | |
| SCHEMBL25231131 | 0.84 | HTR2C (0.51) | HTR2CKDM1AMAOAMAOBSLC6A2 | |
| SCHEMBL28950360 | 0.82 | SLC6A2 (0.50) | HTR2CKDM1AMAOASLC6A2NPC1 | |
| SCHEMBL25222944 | 0.81 | KDM1A (0.42) | KDM1AMAOAMAOBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003110-B | Aryl beta-aminoketone compound and preparation method thereof | 南京工业大学 | 2022-09-06 | — | — | CN | disclosed |