Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.62 |
| ▸ | KDM1A | O60341 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091037 | 1.00 | HTR2C (0.62) | HTR2CKDM1AMAOAMAOBHTR2A | |
| SCHEMBL6227343 | 0.87 | HTR2C (0.61) | HTR2CKDM1AMAOAMAOBHTR2A | |
| SCHEMBL6227345 | 0.87 | HTR2C (0.61) | HTR2CKDM1AMAOAMAOBHTR2A | |
| SCHEMBL2435013 | 0.86 | HTR2C (0.59) | HTR2CKDM1AMAOAMAOBMAPT | |
| SCHEMBL28829967 | 0.84 | HTR2C (0.58) | HTR2CKDM1AMAOAMAOBMAPT | |
| SCHEMBL15797925 | 0.81 | HTR2C (0.54) | HTR2CKDM1AMAOAMAOBMAPT | |
| SCHEMBL2437089 | 0.81 | HTR2C (0.54) | HTR2CKDM1AMAOAMAOBMAPT | |
| SCHEMBL9380414 | 0.80 | ALOX5 (0.58) | HTR2CKDM1AMAOAMAOBHTR2A | |
| SCHEMBL2434808 | 0.80 | HTR2C (0.52) | HTR2CKDM1AMAOAMAOBMAPT | |
| SCHEMBL9380418 | 0.80 | ALOX5 (0.58) | HTR2CKDM1AMAOAMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163761-B2 | Methods and compositions for treating disorders | HYDRA BIOSCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |