Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 6/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.59 |
| ▸ | CAMKK2 | Q96RR4 | 6/20 | 0.59 |
| ▸ | INSR | P06213 | 4/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616059 | 0.88 | HRH3 (0.57) | CHUKMAPK8CAMKK2INSRCHEK1 | |
| SCHEMBL13162039 | 0.88 | CHUK (0.53) | CHUKMAPK8CAMKK2INSRPARP1 | |
| SCHEMBL28074495 | 0.83 | CHUK (0.56) | CHUKMAPK8CAMKK2INSRGRM2 | |
| SCHEMBL16935281 | 0.82 | EZH2 (0.51) | CHUKMAPK8CAMKK2INSR | |
| SCHEMBL28187184 | 0.78 | CYP2A13 (0.52) | CHUKMAPK8CAMKK2INSRJAK2 | |
| SCHEMBL12273972 | 0.78 | CHUK (0.52) | CHUKMAPK8CAMKK2INSRPARP1 | |
| SCHEMBL13162661 | 0.76 | HTT (0.54) | CHUKMAPK8CAMKK2HRH3 | |
| SCHEMBL13634492 | 0.76 | SMN1; SMN2 (0.50) | HRH3NOS1NOS3NOS2 | |
| SCHEMBL27811750 | 0.75 | SMN1; SMN2 (0.47) | CHUKMAPK8CAMKK2INSRHRH3 | |
| SCHEMBL13270379 | 0.74 | USP2 (0.47) | CHUKMAPK8CAMKK2INSRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037360-B | Pyridione derivatives and its production and use | 四川大学 | 2016-08-17 | — | — | CN | disclosed |