Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 3/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.56 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.56 |
| ▸ | INSR | P06213 | 2/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | STK4 | Q13043 | 1/20 | 0.47 |
| ▸ | STK3 | Q13188 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719688 | 0.83 | HRH3 (0.59) | SMN1; SMN2LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL28830139 | 0.83 | CHUK (0.59) | CHUKMAPK8CAMKK2INSRCHEK1 | |
| SCHEMBL4164833 | 0.82 | NCF1 (0.61) | CHEK1NOS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29864585 | 0.82 | NCF1 (0.61) | CHEK1NOS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4649682 | 0.80 | PDE4B (0.69) | PDCD1CD274PDE4BSMN1; SMN2MAPT | |
| SCHEMBL26180966 | 0.79 | STK4 (0.50) | CHUKMAPK8CAMKK2INSRSTK4 | |
| SCHEMBL27955760 | 0.79 | PARP1 (0.52) | CHUKMAPK8CAMKK2INSRCHEK1 | |
| SCHEMBL13162039 | 0.74 | CHUK (0.53) | CHUKMAPK8CAMKK2INSRNOS1 | |
| SCHEMBL30823477 | 0.74 | CD274 (0.51) | CHUKMAPK8CAMKK2INSRPDCD1 | |
| SCHEMBL2912823 | 0.73 | HPGD (0.64) | NOS1SMN1; SMN2ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037360-B | Pyridione derivatives and its production and use | 四川大学 | 2016-08-17 | — | — | CN | disclosed |