SCHEMBL28830508

SCHEMBL28830508

OCCC[C@@H](CO)c1ccc(Br)cc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34
ALOX5 P09917 1/20 0.33
CYP1A2 P05177 1/20 0.33
PYCR1 P32322 1/20 0.33
CYP2A6 P11509 1/20 0.32
CNR1 P21554 2/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
ALOX15 P16050 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28830511 1.00 HTR2A (0.34) HTR2AALOX5CYP1A2PYCR1CYP2A6
SCHEMBL17532645 0.85 NR1I2 (0.41) HTR2AALOX5CYP1A2PYCR1
SCHEMBL15786506 0.85 HTR2A (0.44) HTR2AALOX5CYP1A2MEN1KMT2A
SCHEMBL11856343 0.85 NR1I2 (0.37) ALOX5CYP1A2PYCR1KMT2A
SCHEMBL19262248 0.85 KMT2A (0.33) HTR2AALOX5CYP1A2PYCR1CNR1
SCHEMBL537267 0.83 CYP2A6 (0.42) HTR2AALOX5CYP1A2CYP2A6CNR1
SCHEMBL28830504 0.80 GABBR2 (0.41) CYP1A2MEN1KMT2A
SCHEMBL28830454 0.80 CHRNA7 (0.39) ALOX5CNR1
SCHEMBL28830550 0.80 GABBR2 (0.40)
SCHEMBL28830505 0.80 GABBR2 (0.41) CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957304-B Chiral 1, 5-diborane compound and synthetic method and application thereof 浙江大学 2024-06-21 CN disclosed
CN-114957304-A Chiral 1, 5-diborane compound and synthesis method and application thereof 浙江大学 2022-08-30 CN disclosed