Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107214 | 0.88 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL8357913 | 0.86 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Alcohol SCHEMBL28427960 | 0.86 | TSHR (0.70) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL106212 | 0.84 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2851828 | 0.84 | TSHR (0.74) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL26117 | 0.84 | — | — | |
| SCHEMBL669923 | 0.82 | TSHR (0.85) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Propene SCHEMBL27674340 | 0.82 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL31339001 | 0.82 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Phosphine SCHEMBL31268105 | 0.82 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336120-B | Nano SiO with surface migration 2 Preparation method of microsphere and nano SiO 2 | 安庆北化大科技园有限公司 | 2022-09-09 | — | — | CN | disclosed |