Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 15/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681084 | 0.76 | MAPK1 (0.70) | MAPK1 | |
| SCHEMBL22553171 | 0.75 | PIK3CG (0.54) | MAPK1ALKPIK3CGPIK3CAPIK3CD | |
| SCHEMBL30436722 | 0.72 | ALK (0.41) | MAPK1ALK | |
| SCHEMBL20145777 | 0.71 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL20145784 | 0.70 | MAPK1 (0.73) | MAPK1 | |
| SCHEMBL16679270 | 0.70 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16679272 | 0.70 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16680783 | 0.69 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16680781 | 0.69 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16679301 | 0.69 | MAPK1 (1.00) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |