Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437026 | 0.79 | MKNK1 (0.50) | MAPK1BRD4 | |
| SCHEMBL30437354 | 0.76 | GRIN2B (0.46) | ACACBACACAPARP1 | |
| SCHEMBL30436768 | 0.73 | MKNK1 (0.52) | ACACBACACAJAK1JAK3 | |
| SCHEMBL30436871 | 0.73 | JAK3 (0.51) | MAPK1ACACBACACAPARP1JAK1 | |
| SCHEMBL30436844 | 0.72 | NR4A2 (0.49) | ACACBACACAAXLPARP1 | |
| SCHEMBL28830742 | 0.72 | MAPK1 (0.53) | ALKMAPK1 | |
| SCHEMBL1224892 | 0.69 | GAA (0.50) | — | |
| SCHEMBL20936832 | 0.67 | ALDH1A1 (0.44) | ALKUSP30MAPK1BRD4 | |
| SCHEMBL29638555 | 0.67 | RPS6KB1 (0.40) | — | |
| SCHEMBL19998629 | 0.67 | USP30 (0.46) | ALKUSP30MAPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102549-B | 5-Aldehyde heterocyclic amide compound and application thereof | 暨南大学 | 2025-02-11 | — | — | CN | claimed |
| CN-116102549-A | 5-aldehyde heterocyclic amide compound and application thereof | 暨南大学 | 2023-05-12 | — | — | CN | claimed |