SCHEMBL28830947

SCHEMBL28830947

NC1CCCCN(c2cccnc2)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.47
DRD2 P14416 2/20 0.46
DRD3 P35462 1/20 0.46
CYP11B2 P19099 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.43
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
CYP11B1 P15538 3/20 0.41
CHRNB2 P17787 3/20 0.40
CHRNA4 P43681 3/20 0.40
CHRNA7 P36544 1/20 0.40
HDAC1 Q13547 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29819531 1.00 PIM1 (0.47) PIM1DRD2DRD3CYP11B2L3MBTL1
SCHEMBL28830946 1.00 PIM1 (0.47) PIM1DRD2DRD3CYP11B2L3MBTL1
SCHEMBL12527658 1.00 PIM1 (0.47) PIM1DRD2DRD3CYP11B2L3MBTL1
Trifluoroacetic Acid SCHEMBL12494146 0.89 DPP4 (0.49) PIM1DRD2DRD3CYP11B2L3MBTL1
SCHEMBL12493905 0.82 KMT2A (0.46) DRD2DRD3L3MBTL1ALDH1A1CA1
SCHEMBL12493909 0.82 KMT2A (0.46) DRD2DRD3L3MBTL1ALDH1A1CA1
SCHEMBL12493668 0.80 MEN1 (0.44) DRD2DRD3ALDH1A1CA1CA2
SCHEMBL29187462 0.80 L3MBTL1 (0.49) DRD2DRD3CYP11B2L3MBTL1CYP11B1
SCHEMBL30777490 0.80 L3MBTL1 (0.49) DRD2DRD3CYP11B2L3MBTL1CYP11B1
SCHEMBL29187464 0.80 L3MBTL1 (0.49) DRD2DRD3CYP11B2L3MBTL1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957385-A Dipeptide compound containing beta-lactam ring, preparation method and application thereof 浙大城市学院 2022-08-30 CN disclosed