Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 2/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301038 | 0.85 | LPL (0.43) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL4232484 | 0.85 | LPL (0.43) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL17442380 | 0.83 | JAK2 (0.36) | LPLLIPGANPEPLAP3 | |
| SCHEMBL29486902 | 0.82 | LPL (0.41) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL22799649 | 0.81 | LPL (0.38) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL18865928 | 0.81 | LPL (0.40) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL29691041 | 0.81 | LPL (0.40) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL17442039 | 0.80 | LPL (0.37) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL17618242 | 0.80 | LPL (0.42) | LPLLIPGP4HBANPEPLAP3 | |
| SCHEMBL29469030 | 0.80 | LPL (0.42) | LPLLIPGP4HBANPEPLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233605-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-115028631-A | Triazole pyrimidine derivative, and pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-09-09 | — | — | CN | disclosed |