Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819736 | 1.00 | HDAC6 (0.55) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14000535 | 0.92 | HDAC6 (0.63) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12408907 | 0.88 | HDAC6 (0.45) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2242175 | 0.88 | NPC1 (0.65) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29819658 | 0.88 | NPC1 (0.65) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29819557 | 0.88 | NPC1 (0.65) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1026589 | 0.86 | HDAC6 (0.54) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL25811147 | 0.85 | HDAC6 (0.51) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10221379 | 0.85 | HDAC6 (0.56) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3288218 | 0.85 | NPC1 (0.66) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957152-B | Synthesis method of benzoxazole compound | 湖南第一师范学院 | 2023-11-17 | — | — | CN | disclosed |
| CN-114957152-A | Synthetic method of benzoxazole compound | 湖南第一师范学院 | 2022-08-30 | — | — | CN | disclosed |