Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | GFER | P55789 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819557 | 0.97 | NPC1 (0.65) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL29819658 | 0.97 | NPC1 (0.65) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL2242175 | 0.97 | NPC1 (0.65) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL15745637 | 0.94 | NPC1 (0.73) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL14947174 | 0.92 | NPC1 (0.75) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL8345323 | 0.92 | NPC1 (0.57) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL29881441 | 0.92 | NPC1 (0.57) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL11134813 | 0.92 | NPC1 (0.57) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL3288472 | 0.91 | NPC1 (0.78) | NPC1RAB9AGFERSMN1; SMN2KDM4E | |
| SCHEMBL24295191 | 0.88 | SMN1; SMN2 (0.65) | NPC1RAB9AGFERSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723114-B1 | Methods and systems for detection of radionuclides | CLEMSON UNIVERSITY (US) | 2010-05-25 | — | — | US | disclosed |
| EP-1032850-B1 | SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS | MINNESOTA MINING & MFG (US) | 2003-12-17 | — | — | EP | disclosed |
| EP-1183554-A1 | IN-SITU RADIOACTIVITY DETECTION | 3M Innovative Properties Company (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000077545-A1 | IN-SITU RADIOACTIVITY DETECTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6139749-A | CONTACTING ENVIRONMENTAL FLUID WITH COMPOSITE SHEET MATERIAL COMPRISING SEPARATORS AND SCINTILLATORS ENTRAPPED IN POROUS MATRIX OR MEMBRANE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1032850-A1 | SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999027387-A1 | SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |