Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309009 | 0.82 | PLK1 (0.50) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL11999824 | 0.77 | PLK1 (0.54) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL12184928 | 0.75 | PLK1 (0.53) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL27404398 | 0.75 | MEN1 (0.38) | PLK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11962155 | 0.73 | PLK1 (1.00) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL16503568 | 0.72 | CYP3A4 (0.58) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL15032873 | 0.72 | PLK1 (0.50) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL13085692 | 0.72 | PLK1 (0.50) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL2796317 | 0.72 | PLK1 (0.74) | PLK1ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL30329933 | 0.72 | RAB9A (0.57) | PLK1ALDH1A1KDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922396-B | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | 建新公司 | 2022-08-05 | — | — | CN | disclosed |