Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24175977 | 0.87 | TACR1 (0.41) | TACR1STSKLK7JAK2JAK1 | |
| SCHEMBL28566941 | 0.83 | STS (0.38) | TACR1STSKLK7JAK2JAK1 | |
| SCHEMBL28588244 | 0.83 | PRMT5 (0.37) | TACR1SMN1; SMN2STSKLK7JAK2 | |
| SCHEMBL30089180 | 0.79 | TACR1 (0.40) | TACR1NPC1RAB9ASMN1; SMN2STS | |
| SCHEMBL24175974 | 0.79 | TACR1 (0.40) | TACR1NPC1RAB9ASMN1; SMN2STS | |
| SCHEMBL24998912 | 0.79 | TACR1 (0.38) | TACR1NPC1RAB9ASMN1; SMN2STS | |
| SCHEMBL19614476 | 0.79 | TACR1 (0.45) | TACR1 | |
| SCHEMBL19614478 | 0.79 | TACR1 (0.45) | TACR1 | |
| SCHEMBL703326 | 0.79 | TACR1 (0.45) | TACR1 | |
| SCHEMBL19838986 | 0.78 | TACR1 (0.46) | TACR1STSKLK7L3MBTL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661398-B | Spiro-lactam and di-spiro-lactam NMDA receptor modulators and uses thereof | 阿普廷伊克斯股份有限公司 | 2022-07-05 | — | — | CN | disclosed |