Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704275 | 1.00 | PRMT5 (0.44) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL24339668 | 0.91 | AAK1 (0.42) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL18179491 | 0.89 | PRMT5 (0.43) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL29977526 | 0.88 | PRMT5 (0.42) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL24703836 | 0.88 | PRMT5 (0.42) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL16809887 | 0.84 | PRMT5 (0.42) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL29918701 | 0.84 | PRMT5 (0.42) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL29279177 | 0.84 | PRMT5 (0.42) | PRMT5WDR77AAK1USP30BACE1 | |
| SCHEMBL30331654 | 0.82 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL31645840 | 0.82 | PRMT5 (0.42) | PRMT5WDR77AAK1USP30BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003671-A | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2022-09-02 | — | — | CN | disclosed |