Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868425 | 0.95 | CA2 (0.42) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| Acetic Acid SCHEMBL28810115 | 0.92 | HDAC1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL15442717 | 0.90 | CA2 (0.47) | SLC1A2SLC1A1CA2CA1CHRM1 | |
| SCHEMBL10757976 | 0.88 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8026851 | 0.86 | HDAC1 (0.44) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| Maleic Acid SCHEMBL10423709 | 0.86 | HCAR2 (0.49) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| Acetic Acid SCHEMBL2592024 | 0.85 | CA2 (0.56) | SLC1A2SLC1A1CA2CA1TDP1 | |
| SCHEMBL15443024 | 0.85 | CA2 (0.55) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL27868585 | 0.84 | CHRM1 (0.52) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL15442728 | 0.83 | CA2 (0.53) | GRIK1GRIK2CA2CA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106133009-A | Two grades of suspending agents for suspension polymerization | 辛色姆（英国）有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-106133009-B | Second level suspending agent for suspension polymerization | 辛色姆（英国）有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-106133009-A | Two grades of suspending agents for suspension polymerization | 辛色姆（英国）有限公司 | 2016-11-16 | — | — | CN | disclosed |