Methane

Methane

SCHEMBL28832437

C.CCC1(CC)CC(c2ccccc2)=CC(C)(C)C1(N)N

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
KDM1A O60341 6/20 0.33
MAOA P21397 6/20 0.33
MAOB P27338 6/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28793204 0.80 NPC1 (0.40) NPC1RAB9AKDM1AMAOAMAOB
Methane SCHEMBL28093987 0.75 NPC1 (0.36) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL12200085 0.74 KDM1A (0.39) NPC1RAB9AKDM1AMAOAMAOB
SCHEMBL21242653 0.72 NPC1 (0.43) NPC1RAB9AKDM1AMAOAMAOB
Methane SCHEMBL28950908 0.69 KDM1A (0.30) KDM1AMAOAMAOB
SCHEMBL7032038 0.65 NPC1 (0.41) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL9842987 0.61 NPC1 (0.36) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL28096454 0.60 NPC1 (0.47) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL14491867 0.60 NPC1 (0.43) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL28972364 0.58 HDAC1 (0.39) NPC1RAB9AALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106133036-A Prepreg and fibre reinforced composites 东丽株式会社 2016-11-16 CN disclosed