Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2889288 | 0.99 | S1PR1 (0.33) | S1PR1SSTR4S1PR3 | |
| SCHEMBL2109252 | 0.78 | S1PR1 (0.35) | S1PR1SSTR4S1PR3 | |
| SCHEMBL9289485 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2111977 | 0.77 | S1PR1 (0.34) | S1PR1SSTR4S1PR3 | |
| Hydrochloric Acid SCHEMBL1327128 | 0.76 | — | — | |
| SCHEMBL10200081 | 0.75 | CDK7 (0.37) | S1PR1SSTR4S1PR3 | |
| SCHEMBL2888604 | 0.74 | S1PR1 (0.42) | S1PR1SSTR4S1PR3 | |
| SCHEMBL10200750 | 0.74 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL10200562 | 0.74 | S1PR1 (0.33) | S1PR1SSTR4S1PR3 | |
| Hydrochloric Acid SCHEMBL2111829 | 0.74 | CDK7 (0.36) | S1PR1SSTR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213675-B1 | PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2013-08-14 | — | — | EP | claimed |
| US-8329687-B2 | Pyridooxazepine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-12-11 | — | — | US | claimed |
| US-20100286120-A1 | PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-11 | — | — | US | claimed |
| EP-2213675-A1 | PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-08-04 | — | — | EP | claimed |
| EP-2213675-B1 | PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-8329687-B2 | Pyridooxazepine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20100286120-A1 | PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2213675-A1 | PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286120-A1 | PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF | HTR2C, HTR2A, TPH2 | S1PR1 129/4885SSTR4 512/4885S1PR3 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.