Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cytarabine 5'-Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 3/20 | 0.60 |
| ▸ | ST6GAL1 | P15907 | 8/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cytarabine 5'-Phosphate SCHEMBL17934719 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL14669262 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL207204 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL18785109 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL2681941 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL16189 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL6115643 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL11217191 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL284602 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA | |
| Cytarabine 5'-Phosphate SCHEMBL20277485 | 0.91 | P2RY2 (0.69) | P2RY2ST6GAL1TSHRGLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507538-B | Compositions and methods for cancer immunotherapy | 艾杜罗生物科技公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-106358440-A | Factor vii conjugates | 诺和诺德保健股份有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-106029106-A | Coagulation factor IX conjugates | 诺和诺德保健股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105979972-A | Factor viii conjugates | 诺和诺德股份有限公司 | 2016-09-28 | — | — | CN | disclosed |