Cytarabine 5'-Phosphate

Cytarabine 5'-Phosphate

SCHEMBL17934719

Nc1ccn([C@@H]2O[C@H](COP(=O)(O)O)C(O)[C@@H]2O)c(=O)n1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 7/20 0.69
LMNA P02545 1/20 0.69
THRB P10828 1/20 0.69
MTOR P42345 1/20 0.69
MDM2 Q00987 1/20 0.69
NCOA1 Q15788 1/20 0.69
NCOA3 Q9Y6Q9 1/20 0.69
TSHR P16473 1/20 0.67
GLA P06280 1/20 0.67
P2RY6 Q15077 3/20 0.64
ST6GAL1 P15907 5/20 0.64
P2RY4 P51582 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytarabine 5'-Phosphate SCHEMBL20277485 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL14669262 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL207204 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL284602 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL11217191 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL16189 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL6115643 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL2681941 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL18785109 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL29450798 1.00 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279266-A1 POLISHING LIQUID COMPOSITION FOR SILICON OXIDE FILMS KAO CORPORATION (JP) 2023-09-07 US disclosed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US disclosed
US-20160205924-A1 METHODS OF INCREASING THE VIABILITY OR LONGEVITY OF AN ORGAN OR ORGAN EXPLANT MODERNATX, INC. 2016-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 P2RY2 1037/4885LMNA 3032/4885THRB 4145/4885
US-20160205924-A1 METHODS OF INCREASING THE VIABILITY OR LONGEVITY OF AN ORGAN OR ORGAN EXPLANT RNGTT, L3MBTL3, RNASE1 P2RY2 3344/4885LMNA 281/4885THRB 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.