SCHEMBL28833113

SCHEMBL28833113

CCCCCn1nc(CO)cc1O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.38
CNR2 P34972 9/20 0.38
SLC9A1 P19634 1/20 0.36
MPO P05164 1/20 0.36
HCAR3 P49019 1/20 0.35
ESR1 P03372 1/20 0.35
SMPD1 P17405 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402142 0.81 ESR1 (0.40) CNR1CNR2SLC9A1MPOHCAR3
SCHEMBL31287800 0.80 SLC9A1 (0.39) CNR1CNR2SLC9A1MPOHCAR3
SCHEMBL11500127 0.80 KDM4E (0.44) CNR1CNR2SLC9A1MPOHCAR3
SCHEMBL23402228 0.80 ESR1 (0.39) CNR1CNR2SLC9A1MPOHCAR3
SCHEMBL23401066 0.80 ESR1 (0.39) CNR1CNR2SLC9A1MPOHCAR3
SCHEMBL23533806 0.79 KDM4E (0.42) CNR1CNR2SLC9A1SMPD1
SCHEMBL11329735 0.77 CNR1 (0.33) CNR1CNR2SLC9A1MPOHCAR3
SCHEMBL23401138 0.76 NPC1 (0.37) CNR1CNR2HCAR3ESR1
SCHEMBL23401680 0.76 ESR1 (0.37) CNR1CNR2SLC9A1MPOHCAR3
SCHEMBL9879787 0.76 KDM4E (0.36) CNR1CNR2SLC9A1MPOHCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104059020-B The preparation method of 1-aryl-5-hydroxypyrazoles 湖南海利常德农药化工有限公司 2016-08-31 CN disclosed