Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818781 | 0.88 | TP53 (0.54) | PKMTP53ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11814079 | 0.82 | TP53 (0.64) | TP53ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL27766830 | 0.81 | GAA (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7591412 | 0.80 | TP53 (0.51) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8195390 | 0.80 | TP53 (0.51) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21181224 | 0.79 | TP53 (0.50) | PKMTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10757315 | 0.79 | TP53 (0.50) | TP53ALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL8662292 | 0.79 | CYP3A4 (0.50) | TP53ALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL29261800 | 0.79 | TP53 (0.50) | PKMTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL132541 | 0.77 | CYP3A4 (0.65) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980386-A | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2016-09-28 | — | — | CN | disclosed |