Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591412 | 0.84 | TP53 (0.51) | CYP3A4SMN1; SMN2TP53TDP1CASR | |
| SCHEMBL8195390 | 0.84 | TP53 (0.51) | CYP3A4SMN1; SMN2TP53TDP1CASR | |
| SCHEMBL29261800 | 0.83 | TP53 (0.50) | CYP3A4SMN1; SMN2TP53TDP1CASR | |
| SCHEMBL21181224 | 0.83 | TP53 (0.50) | CYP3A4SMN1; SMN2TP53TDP1CASR | |
| SCHEMBL10757315 | 0.83 | TP53 (0.50) | CYP3A4SMN1; SMN2TP53TDP1CASR | |
| SCHEMBL8663273 | 0.82 | SMN1; SMN2 (0.54) | CYP3A4SMN1; SMN2LOXL2MEN1KMT2A | |
| SCHEMBL7691526 | 0.81 | LOXL2 (0.61) | CYP3A4SMN1; SMN2LOXL2MEN1KMT2A | |
| SCHEMBL132541 | 0.81 | CYP3A4 (0.65) | CYP3A4SMN1; SMN2TP53TDP1CASR | |
| SCHEMBL29944162 | 0.81 | CYP3A4 (0.65) | CYP3A4SMN1; SMN2TP53TDP1CASR | |
| SCHEMBL629680 | 0.81 | LOXL2 (0.61) | CYP3A4SMN1; SMN2LOXL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770380-A | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold | UNIVERSITY OF PITTSBURGH (US) | 1998-06-23 | — | — | US | disclosed |