Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886925 | 1.00 | F10 (0.40) | F10PTGS2MTORHTTKDM4E | |
| SCHEMBL29887039 | 0.80 | MAPT (0.48) | HTTKDM4ELMNAGLAKMT2A | |
| SCHEMBL28833540 | 0.80 | MAPT (0.48) | HTTKDM4ELMNAGLAKMT2A | |
| SCHEMBL17151141 | 0.75 | PTGS2 (0.46) | F10PTGS2MTORKDM4EKMT2A | |
| SCHEMBL848002 | 0.74 | POLB (0.48) | F10PTGS2KDM4ELMNAKMT2A | |
| SCHEMBL20180814 | 0.74 | F10 (0.47) | F10PTGS2MTOR | |
| SCHEMBL25033227 | 0.72 | PTGS2 (0.46) | F10PTGS2MTOR | |
| SCHEMBL19841832 | 0.72 | LRRK2 (0.43) | F10PTGS2MTOR | |
| SCHEMBL17148219 | 0.72 | F10 (0.44) | F10PTGS2MTOR | |
| SCHEMBL29887105 | 0.70 | MAPT (0.49) | HTTKDM4EGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114981251-A | Diphenyl furan derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |