Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 19/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.67 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873650 | 0.86 | PIK3CB (0.73) | PIK3CBPIK3CAPIK3CDPIK3CGPRKDC | |
| SCHEMBL1638092 | 0.82 | PIK3CB (0.81) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL1638294 | 0.82 | PIK3CB (0.84) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL27873647 | 0.81 | PIK3CB (0.73) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL1639053 | 0.80 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL28095884 | 0.78 | PIK3CB (0.48) | PIK3CBPIK3CAPIK3CDPIK3CGPRKDC | |
| SCHEMBL28095991 | 0.78 | PIK3CB (0.48) | PIK3CBPIK3CAPIK3CDPIK3CGPRKDC | |
| SCHEMBL1638384 | 0.78 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL1638807 | 0.77 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL1636961 | 0.77 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447657-B | There is the chromene ketone derivatives of anti-tumor activity | 阿斯利康(瑞典)有限公司 | 2016-08-17 | — | — | CN | disclosed |