Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 18/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | ERN2 | Q76MJ5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095884 | 0.90 | PIK3CB (0.48) | PIK3CBPIK3CDPIK3CAPIK3CGPRKDC | |
| SCHEMBL27873587 | 0.82 | PIK3CB (0.50) | PIK3CBPIK3CDPIK3CAPIK3CGPRKDC | |
| SCHEMBL28095513 | 0.82 | PIK3CA (0.48) | PIK3CDPIK3CAPIK3CGPRKDCP2RY12 | |
| SCHEMBL28095889 | 0.82 | PIK3CB (0.67) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL28833467 | 0.78 | PIK3CB (0.67) | PIK3CBPIK3CDPIK3CAPIK3CGPRKDC | |
| SCHEMBL1639079 | 0.77 | PIK3CB (0.60) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL27873586 | 0.76 | PIK3CB (0.51) | PIK3CBPIK3CDPIK3CAPIK3CGPRKDC | |
| SCHEMBL1637732 | 0.76 | PIK3CB (0.56) | PIK3CBPIK3CDPIK3CAPIK3CGPRKDC | |
| SCHEMBL1639036 | 0.74 | PIK3CB (0.70) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL1639091 | 0.74 | PIK3CB (0.73) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447657-B | There is the chromene ketone derivatives of anti-tumor activity | 阿斯利康(瑞典)有限公司 | 2016-08-17 | — | — | CN | disclosed |