Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.51 |
| ▸ | CDK4 | P11802 | 7/20 | 0.50 |
| ▸ | CCND1 | P24385 | 7/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202125 | 0.95 | P2RX7 (0.53) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL5791630 | 0.95 | P2RX7 (0.53) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL5638243 | 0.83 | CDK4 (0.53) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL18856954 | 0.83 | HTR2C (0.56) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL18856949 | 0.82 | HTR2A (0.55) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL5792293 | 0.82 | P2RX7 (0.53) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL9231907 | 0.81 | HTR2A (0.54) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL5991839 | 0.81 | HTR2C (0.54) | HTR2AHTR2CP2RX7CDK4CCND1 | |
| SCHEMBL14274534 | 0.80 | PLG (0.49) | HTR2AHTR2CCDK4CCND1PLG | |
| SCHEMBL22930089 | 0.80 | HTR2C (0.60) | HTR2AHTR2CP2RX7CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103977004-B | The medicinal usage of indole piperazine derivative | 复旦大学 | 2016-08-10 | — | — | CN | disclosed |