O-Tolylamine

O-Tolylamine

SCHEMBL28833563

CCCCCCN.Cc1ccccc1N

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
DNM1 Q05193 8/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TSHR P16473 1/20 0.50
EPHX1 P07099 1/20 0.50
TLR8 Q9NR97 4/20 0.48
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
SKP2 Q13309 1/20 0.42
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTR2A P28223 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Tolylamine SCHEMBL7641113 1.00 CYP3A4 (0.56) CYP3A4TDP1DNM1ALDH1A1MEN1
Octane SCHEMBL28067829 0.92 CYP3A4 (0.65) CYP3A4TDP1ALDH1A1TSHRTLR8
Decylamine SCHEMBL28248156 0.88 DNM1 (0.59) CYP3A4DNM1ALDH1A1MEN1KMT2A
Octadecylamine SCHEMBL29155792 0.88 DNM1 (0.59) DNM1ALDH1A1MEN1KMT2ATSHR
Dodecylamine SCHEMBL11314986 0.86 DNM1 (0.61) DNM1ALDH1A1MEN1KMT2ATSHR
O-Tolylamine SCHEMBL3542029 0.86 CYP3A4 (0.68) CYP3A4TDP1ALDH1A1TSHRCYP1A2
O-Xylene SCHEMBL28101428 0.86 DNM1 (0.55) DNM1ALDH1A1MEN1KMT2ATSHR
Dodecylamine SCHEMBL8912921 0.85 DNM1 (0.46) CYP3A4DNM1ALDH1A1MEN1KMT2A
O-Tolylamine SCHEMBL3960895 0.81 CYP3A4 (0.75) CYP3A4TDP1ALDH1A1MEN1KMT2A
O-Tolylamine SCHEMBL28267965 0.81 CYP3A4 (0.75) CYP3A4TDP1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105934448-B (methyl) acrylate compounds, (methyl) acrylic copolymer and include its photosensitive polymer combination 三菱瓦斯化学株式会社 2018-02-09 CN disclosed
CN-105934448-A (meth)acrylate compound, (meth)acrylic copolymer and photosensitive resin composition containing same 三菱瓦斯化学株式会社 2016-09-07 CN disclosed