Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833625 | 1.00 | BTK (0.49) | BTKMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL4755107 | 0.84 | KMT2A (0.52) | BTKMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL16764325 | 0.84 | ANO1 (0.57) | BTKLMNAMAPTSMN1; SMN2 | |
| SCHEMBL16764326 | 0.84 | ANO1 (0.57) | BTKLMNAMAPTSMN1; SMN2 | |
| SCHEMBL23080971 | 0.81 | OPRL1 (0.42) | BTKMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4342706 | 0.74 | TAAR1 (0.66) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15054786 | 0.74 | TAAR1 (0.66) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3647453 | 0.73 | CRHR1 (0.54) | MEN1KMT2AALDH1A1RECQLNPSR1 | |
| SCHEMBL3487240 | 0.73 | POLB (0.56) | MEN1KMT2ASMN1; SMN2NPC1EPHX1 | |
| SCHEMBL28324102 | 0.72 | CHEK1 (0.41) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960404-A | Inhibitors of bruton's tyrosine kinase | 药品循环有限责任公司 | 2016-09-21 | — | — | CN | disclosed |