Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylaminoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108953 | 0.96 | CYP1A2 (0.44) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL37853 | 0.89 | MAPT (0.33) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Diethylaminoethanol SCHEMBL10946268 | 0.86 | NPSR1 (0.48) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Diethylaminoethanol SCHEMBL10946251 | 0.86 | NPSR1 (0.48) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL27735583 | 0.85 | KCNH2 (0.37) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL29691337 | 0.84 | NPSR1 (0.40) | CYP2C9NPSR1USP2PAOXCYP2D6 | |
| Trolamine SCHEMBL11787722 | 0.84 | CA1 (0.32) | — | |
| SCHEMBL28672601 | 0.84 | MAPT (0.34) | — | |
| Diethylaminoethanol SCHEMBL5025241 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Diethylaminoethanol SCHEMBL5027761 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP2C9HPGDMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867830-A | Particulate fabric care compositions | 宝洁公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-113980744-A | Color fixing softener and preparation method thereof | 广州南顺清洁用品有限公司 | 2022-01-28 | — | — | CN | disclosed |