Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595800 | 1.00 | KCNA3 (0.34) | KCNA3CHRM3ALDH1A1GAACHRM2 | |
| SCHEMBL20595723 | 1.00 | KCNA3 (0.34) | KCNA3CHRM3ALDH1A1GAACHRM2 | |
| SCHEMBL15412693 | 0.90 | ATM (0.36) | LMNA | |
| SCHEMBL15412695 | 0.90 | ATM (0.36) | LMNA | |
| SCHEMBL15412932 | 0.90 | ATM (0.36) | LMNA | |
| SCHEMBL17923226 | 0.88 | CHRM2 (0.38) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL17941193 | 0.88 | CHRM2 (0.38) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL17923217 | 0.88 | CHRM2 (0.38) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL30899499 | 0.87 | CHRM2 (0.40) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL23298053 | 0.81 | CYP11B1 (0.32) | CHRM3ALDH1A1CHRM2CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873020-B | RAS inhibitors | 锐新医药公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-117500811-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |