SCHEMBL15412693

SCHEMBL15412693

O=C[C@@H]1CCCN1C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 1/20 0.35
SLC6A1 P30531 4/20 0.35
SLC6A11 P48066 1/20 0.35
PREP P48147 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15412932 1.00 ATM (0.36) ATML3MBTL1LMNASLC6A1SLC6A11
SCHEMBL15412695 1.00 ATM (0.36) ATML3MBTL1LMNASLC6A1SLC6A11
SCHEMBL17923217 0.95 CHRM2 (0.38) LMNA
SCHEMBL17941193 0.95 CHRM2 (0.38) LMNA
SCHEMBL17923226 0.95 CHRM2 (0.38) LMNA
SCHEMBL30899499 0.94 CHRM2 (0.40) LMNA
SCHEMBL28833909 0.90 KCNA3 (0.34) LMNA
SCHEMBL20595723 0.90 KCNA3 (0.34) LMNA
SCHEMBL20595800 0.90 KCNA3 (0.34) LMNA
SCHEMBL10514209 0.83 ATM (0.36) ATML3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031506-A Chiral control 波涛生命科学有限公司 2026-05-15 CN disclosed
US-12583883-B2 Asymmetric auxiliary group WAVE LIFE SCIENCES LTD. (SG) 2026-03-24 US disclosed
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD (SG) 2026-02-26 US disclosed
US-12428442-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2025-09-30 US disclosed
US-20240229026-A1 CHIRAL CONTROL WAVE LIFE SCIENCES LTD. (SG) 2024-07-11 US disclosed
US-20240174710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2024-05-30 US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 US disclosed
EP-4219516-A2 CHIRAL CONTROL Wave Life Sciences Ltd. (SG) 2023-08-02 EP disclosed
WO-2018237194-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2018-12-27 WO disclosed
US-9982257-B2 Chiral control WAVE LIFE SCIENCES LTD. (SG) 2018-05-29 US disclosed
US-9885037-B2 2018-02-06 US disclosed
US-20170275621-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2017-09-28 US disclosed
US-9598458-B2 Asymmetric auxiliary group WAVE LIFE SCIENCES JAPAN, INC. (JP) 2017-03-21 US disclosed
US-20170029445-A1 ASYMMETRIC AUXILIARY GROUP WAVE LIFE SCIENCES JAPAN, INC. (JP) 2017-02-02 US disclosed
US-20150211006-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2015-07-30 US disclosed
US-20150197540-A1 ASYMMETRIC AUXILIARY GROUP WAVE LIFE SCIENCES LTD. (SG) 2015-07-16 US disclosed
EP-2872147-A2 CHIRAL CONTROL Wave Life Sciences Pte. Ltd. (SG) 2015-05-20 EP disclosed
WO-2014012081-A2 CHIRAL CONTROL ONTORII, INC. (US) 2014-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718638-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT ATM 4229/4885L3MBTL1 1497/4885LMNA 434/4885
US-20150197540-A1 ASYMMETRIC AUXILIARY GROUP NIT2, IDH1, HBG2 ATM 2411/4885L3MBTL1 3487/4885LMNA 3240/4885
US-20170275621-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 ATM 4785/4885L3MBTL1 420/4885LMNA 1868/4885
US-20240229026-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 ATM 4785/4885L3MBTL1 420/4885LMNA 1868/4885
US-12583883-B2 Asymmetric auxiliary group AGL, RNMT, NSUN2 ATM 3331/4885L3MBTL1 1449/4885LMNA 1824/4885
US-20170029445-A1 ASYMMETRIC AUXILIARY GROUP NIT2, IDH1, HBG2 ATM 2411/4885L3MBTL1 3487/4885LMNA 3240/4885
US-12428442-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT ATM 4229/4885L3MBTL1 1497/4885LMNA 434/4885
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS NSUN2, NSUN3, NOP2 ATM 4625/4885L3MBTL1 600/4885LMNA 284/4885
US-20150211006-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 ATM 4785/4885L3MBTL1 420/4885LMNA 1868/4885
US-20240174710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS ALKBH1, DUT, RNGTT ATM 4229/4885L3MBTL1 1497/4885LMNA 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.