⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28885388 | 0.98 | TSHR (0.41) | — | |
| SCHEMBL20801668 | 0.93 | TSHR (0.38) | — | |
| SCHEMBL13713461 | 0.93 | TSHR (0.38) | — | |
| SCHEMBL26756098 | 0.93 | TSHR (0.38) | — | |
| SCHEMBL2593332 | 0.93 | TSHR (0.38) | — | |
| Hydrochloric Acid SCHEMBL28078980 | 0.91 | TSHR (0.37) | — | |
| SCHEMBL3121478 | 0.87 | GLRA1 (0.39) | — | |
| SCHEMBL4277520 | 0.86 | HTR2C (0.43) | — | |
| Hydrochloric Acid SCHEMBL7675204 | 0.84 | HTR2C (0.38) | — | |
| Hydrochloric Acid SCHEMBL7675200 | 0.84 | HTR2C (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010527270-A | — | — | 2010-08-12 | — | — | JP | claimed |
| EP-2155276-A2 | MEDICAL DEVICES HAVING ANTIFOULING CHARACTER | Boston Scientific Scimed, Inc. (US) | 2010-02-24 | — | — | EP | claimed |
| WO-2008144392-A2 | MEDICAL DEVICES HAVING ANTIFOULING CHARACTER | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-11-27 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| US-20230407285-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | DOGMA THERAPEUTICS, INC. | 2023-12-21 | — | — | US | disclosed |
| CN-116194084-A | Cleavable lipid compounds, compositions containing the same and uses thereof | 赛诺菲巴斯德有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-11603523-B2 | PCSK9 inhibitors and methods of use thereof | ASTRAZENECA AB (SE) | 2023-03-14 | — | — | US | disclosed |
| CN-115160380-A | Compound capable of controlling CO release rate and preparation method thereof | 西安交通大学医学院第一附属医院 | 2022-10-11 | — | — | CN | disclosed |
| US-20220220122-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2022-07-14 | — | — | US | disclosed |
| EP-3642198-B1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LTD (GB) | 2022-03-16 | — | — | EP | disclosed |
| EP-3911648-A2 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | Astrazeneca AB (SE) | 2021-11-24 | — | — | EP | disclosed |
| EP-3911640-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | Astrazeneca AB (SE) | 2021-11-24 | — | — | EP | disclosed |
| EP-1814976-A2 | PEPTIDOMIMETIC POLYMERS FOR ANTIFOULING SURFACES | Northwestern University (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006055531-A2 | PEPTIDOMIMETIC POLYMERS FOR ANTIFOULING SURFACES | NORTHWESTERN UNIVERSITY (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| US-5521145-A | Iminothiazoline derivatives and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0683160-A1 | Iminothiazoline derivatives and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-11-22 | — | — | EP | disclosed |
| EP-0137145-B1 | NEW CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1988-04-27 | — | — | EP | disclosed |
| US-4604463-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1986-08-05 | — | — | US | disclosed |
| EP-0137145-A1 | New camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1985-04-17 | — | — | EP | disclosed |