Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26756098 | 1.00 | TSHR (0.38) | TSHRCA2ABCB11CYP3A4ADRA2B | |
| SCHEMBL2593332 | 1.00 | TSHR (0.38) | TSHRCA2ABCB11CYP3A4ADRA2B | |
| SCHEMBL13713461 | 1.00 | TSHR (0.38) | TSHRCA2ABCB11CYP3A4ADRA2B | |
| Hydrochloric Acid SCHEMBL28078980 | 0.98 | TSHR (0.37) | TSHRCA2ABCB11CYP3A4ADRA2B | |
| SCHEMBL2883395 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28885388 | 0.91 | TSHR (0.41) | TSHRCA2ALDH1A1HTR2CDGKA | |
| SCHEMBL22689123 | 0.89 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12275693 | 0.89 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5356898 | 0.83 | HTR2C (0.56) | TSHRCA2ABCB11CYP3A4ADRA2B | |
| SCHEMBL23049673 | 0.83 | ALDH1A1 (0.56) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023216533-A1 | INDOLE ALKALOID, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 南京中医药大学 | 2023-11-16 | — | — | WO | disclosed |
| US-10385013-B2 | Micro/nano materials, products obtained by covalently modifying surface of micro/nano materials with hydrophilic materials, and method for making same | CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) | 2019-08-20 | — | — | US | disclosed |
| US-20190077746-A1 | MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME | CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077746-A1 | MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME | PHOSPHO1, PTMS, PAM | TSHR 2276/4885CA2 2925/4885ABCB11 4848/4885 |
| US-10385013-B2 | Micro/nano materials, products obtained by covalently modifying surface of micro/nano materials with hydrophilic materials, and method for making same | PHOSPHO1, PTMS, PAM | TSHR 2276/4885CA2 2925/4885ABCB11 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.